The Complement System is an integral part of the body’s immune system, so called because it enhances (complements) the functional ability of antibodies and phagocytic cells. It plays a key role in protecting the body against invasion of harmful bacteria and contributes to the removal of the body’s own damaged and altered cells.
Activation of the Complement System is a very precisely controlled process that is managed by a series of regulatory proteins.
Deficiencies in the Complement System’s proteins can lead to microbial infections and diseases such as rheumatoid arthritis.
Over-activation of the Complement System can lead to chronic diseases such as age-related macular degeneration, renal and neurological disease.
Complement Therapeutics is dedicated to developing therapeutics that normalise Complement System function to treat a variety of diseases.