Dr Rafiq Hasan
Chief Executive Officer
Rafiq has pursued a highly successful career in the pharma industry globally, including senior positions in ophthalmology with Bayer and Novartis. Most recently as SVP and Global Head of Ophthalmology at Bayer, Rafiq grew the business of Eylea® from launch to over USD 2.5bn in 5 years, including its launch in 5 indications in 3 years.
Dr Dennis Keefe
Chief Scientific Officer
Dennis has over 18 years of experience as a drug developer, holding positions of increasing responsibility at Millenium Pharmaceuticals, Shire Human Genetic Therapies, Stealth Biotherapeutics, and most recently Prothelia, where as CSO he led all preclinical and nonclinical development efforts. Dennis brings a wealth of experience across multiple therapeutic areas, encompassing Autoimmune Disease, Neuromuscular and Neurodegenerative Disease, Neonatology and Ophthalmology, and has significant technical expertise in diverse therapeutic modalities.
Chief Financial Officer
Dominic is a seasoned biopharmaceutical executive with many years experience in the sector and previously served as the finance lead at Autolus Therapeutics through the company’s IPO and NASDAQ listing. He led the MBO and subsequent trade sale of a division of Genzyme Therapeutics UK and prior to that held finance positions with Baxter Healthcare and Zeneca. Dominic is a Chartered Accountant and holds a B.Sc from the London School of Economics.
Dr Parisa Zamiri
Chief Medical Officer
Parisa joins CTx from Graybug Vision, Inc., where she held the position of Chief Medical Officer and was responsible for all clinical, statistics, regulatory and medical affairs activities, successfully completing phase II development of their lead asset for wet age-related macular degeneration. Prior to Graybug, Dr. Zamiri held the position of Vice President, Global Head of Clinical Development and Therapeutic Area Head for Ophthalmology at Novartis Pharmaceuticals where she oversaw the design and execution of Phase 2b-4 clinical trials in ophthalmic indications including dry eye, retinitis pigmentosa, and age-related macular degeneration.
Dr Matthias Hebben
Chief Technology Officer
Matthias joins from Alexion Pharmaceuticals Inc., where he held the position of VP of Pipeline and Technology Development. Prior to that, he was Global Vice President of Technology Development at LogicBio Therapeutics and Director of Gene Therapy Technology and CMC Development at Genethon where he led the development of manufacturing processes for AAV and lentivirus vectors as well as innovative technologies for AAV production improvement.
Dr Rachel Handy
SVP, Development Operations
Rachel has over 25 years of experience within the pharmaceutical industry from having held positions within early drug discovery through to late-stage clinical development with a breadth of knowledge to ensure that quality and data integrity runs through all functions within Complement. Prior to joining Complement Rachel has worked for Merck, AstraZeneca, Cambridge Antibody Technology, Ferring, Vantia, Eleusis and Beckley Psytech and most recently managing her own consultancy company assisting a variety of biotech companies in clinical operations and quality functions.
Dr Mustafa Munye
Mustafa has significant industry experience in the discovery and development of cell and gene therapies gained at GSK and CGTC. He has previously led process and analytical development for AAV, CAR-T and PSC derived cell therapy products to support FIH and late-stage clinical studies. Mustafa serves as a board member of the British Society for Gene and Cell Therapy working in pan-industry/academia working groups to overcome common barriers to translation and commercialisation of Advanced Therapies.
Harry Kwong, MBA
Harry has a biochemistry and biochemical engineering background from Imperial College and UCL. He has diverse experience working in cross-functional and founding teams to build early-stage biotech developing ATMP. He has previously led process development at LIfT Biosciences and later supported the company in fundraising, strategies & operations and orchestrating timely milestone deliveries. Harry completed his MBA in 2021.
Prong holds a Bioprocessing of New Medicines degree from UCL and an Innovation, Entrepreneurship and Management degree from Imperial College London. She has several experiences working in start-ups, including a food biotechnology, an e-commerce platform, as well as Thailand’s first national clinical research organisation.
Prof Simon J. Clark
Simon is the Helmut Ecker Endowed Professor of AMD and leads a research team studying the molecular mechanisms behind AMD. Simon has contributed to a number of advancements in our understanding of how the Complement System is implicated in disease.
Prof Paul Bishop
Paul is a world-leading ophthalmologist and an acknowledged clinical and molecular expert in AMD, as well as an entrepreneur.
Dr Richard Unwin
Richard leads research programmes in Manchester studying protein levels in a range of human diseases, including AMD, identifying novel disease pathways, markers and therapeutic targets.